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Born in Shanghai, China, Yong Wen immigrated to the U.S. at the age of 13. Familiar with both Eastern and Western cultures, he studied engineering as an undergraduate and holds a master's degree in mechanical engineering. Seeking a greater challenge, he transitioned to medical school, where he has practiced nephrology for the past 20 years—a decision he is glad he made. Wen grew up in a society without an official religion, and without much religious influence. His personal philosophy draws from Confucianism, Stoicism, and Buddhism. He prefers to figure things out for himself rather than be indoctrinated, particularly regarding social issues. Lately, he has been intrigued by understanding the physiology behind psychological diseases, and the relationship between hormones, neurotransmitters, emotions, cognition, and behavior.